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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77055 | Lenercept | ||
Lenercept (Ro 45-2081)为一种由可溶性TNF-receptor(p55)与人IgG1 Fc 部分连接形成的重组融合蛋白。 | |||
T77039 | Ipafricept | ||
Ipafricept (OMP-54F28; FZD8-Fc) 是一类重组融合蛋白,由人卷曲 8 受体胞外部分融合到结合Wnt 配体的人IgG1Fc 片段组成。Ipafricept 具有实体瘤抑制活性,耐受性良好。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00820 |
IgG1 Fc Protein, Human, Recombinant (C103S)
Ighg1,IgG1 Fc |
Human | HEK293 Cells |
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1. | |||
TMPK-00759 |
IgG1 Fc Protein, Human, Recombinant
Igh-4,VH7183,IgG1,RGD135... |
Human | HEK293 Cells |
IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues.IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases. | |||
TMPY-05138 |
IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated
IgG1 Fc,Ighg1 |
Human | HEK293 Cells |
IgG1 Fc Protein, Human, Recombinant (C103S), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.1 kDa and the accession number is AAC82527.1. | |||
TMPY-06893 |
IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated
Ighg1,IgG1 Fc |
Human | HEK293 Cells |
IgG1 Fc Protein, Human, Recombinant (C103S, Avi), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.89 kDa and the accession number is AAC82527.1. | |||
TMPY-05037 |
CD3E & CD3G Heterodimer Protein, Mouse, Recombinant (hFc & His)
CD3epsilon,CD3,CD3ε,AI504783,CD3e molecule, epsilon (CD3-TCR... |
Mouse | HEK293 Cells |
CD3E & CD3G Heterodimer Protein, Mouse, Recombinant (C-human IgG1-Fc & His & C-human IgG1-Fc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.4 kDa and the accession number is NP_031674.1&NP_033980.1. | |||
TMPJ-00751 |
IgG4 hFc Protein, Human, Recombinant (aa 99-326)
IgG4 Fc,Ig γ-4 chain C region,Ig gamma-4 c... |
Human | HEK293 Cells |
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetram... | |||
TMPK-01523 |
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)
WAGR,WT33,AWT1,GUD,RMF,WT1,WIT-2,MHC,NPHS4... |
Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1. | |||
TMPK-01534 |
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)
RING12,PSMB9,Proteasome chain 7,RMF,LMP-2,LMP2,MHC,... |
Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... | |||
TMPK-01522 |
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)
RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,WT1,NPHS4... |
Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1. | |||
TMPK-01535 |
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Macropain chain 7,LMP2,Proteasome chain 7,RING12,PS... |
Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma... |